######## Syllabus ######## ************ Imaging data ************ * the structure of raw brain imaging data; * loading, manipulating, showing and saving brain images; * coordinate systems and transforms for brain images; * working with multiple time courses. ***************** Analysis concepts ***************** * writing and running diagnostics; * time-course interpolation to allow for slice-wise acquisition of brain volumes; * cost-functions and numerical optimization for image alignment; * spatial transformations for image alignment: translations, rotations, zooms and shears; * individual variability of sulci and other brain structure; methods of reducing variability by automated alignment and warping; remaining variation and statistical analysis; * smoothing / blurring prior to statistical analysis; cost and benefit; * multiple regression for modeling the effect of the experiment on time courses of brain activity; * specifying a model of neural activity; transformation of neural activity to predicted FMRI signal using a hemodynamic response function; modeling the hemodynamic response; * estimating multiple regression models; hypothesis testing on multiple regression models; the General Linear Model as generalization of multiple regression; * inference on maps of statistics; correction for multiple comparisons; family-wise error; false discovery rate. ********************************************** Collaboration, correctness and reproducibility ********************************************** * collaborating with peers and mentors; * role of working practice in quality, reproducibility, collaboration; * choosing and learning simple tools; * version control with git_; * sharing code with https://github.com; * scripting and coding with Python; * pair coding and code review; * testing; * documentation.